DIM is an indole phytochemical that is a natural metabolite of compounds found in cruciferous vegetables such as broccoli, Brussels sprouts and cabbage. In preclinical studies, DIM has been shown to lead to the preferential formation of estrogen metabolites that are correlated with healthy breast, endometrial, and cervical tissues. This unique property sets DIM apart from other plant nutrients.
As a consequence of DIM’s ability to safely and efficiently increase 2-hydroxy estrogen metabolite levels these unique estrogen metabolites are known to stimulate progesterone production, and compete with testosterone for protein binding. Thus it helps maintain an optimal estrogen/progesterone balance and also helps testosterone remain in its unbound, free and active form which can also be of great benefit to both men and women.
The usual dose for DIM is 25 to 100mg daily for women and 50 to 100mg a day for men. Due to its crystalline structure and poor water solubility the absorption of DIM when given orally is very poor. To overcome this various DIM complexes have been made by several companies in order to increase its oral absorption however 100mg of the DIM-complex only provides 25mg of DIM with the other 75mg being the complexing agent. Therefore two to four capsules are required each day for a therapeutic dose which can become expensive.
The Artisan Chemist has formulated a transdermal DIM cream which is easily absorbed to positively influence estrogen metabolite imbalances as well as reducing estrogen levels themselves.
Directions: Apply 0.5mL to 1mL onto thin skin (inner forearms or inner thighs) ONCE daily or as directed by your health care practitioner.