Azelaic acid 10% Solution

Azelaic acid 10% Solution

Regular price $50.00

DESCRIPTION

Azelaic Acid is a powerful antioxidant that helps unclog pores and refine skin texture. Azelaic acid also significantly lessens factors in skin that lead to redness and bumps.

Research has shown azelaic acid can significantly diminish blemishes, help fade the appearance of post-acne red marks and other discolorations, and reduce the kind of skin sensitivity that leads to redness.

CLINICAL INFORMATION

Azelaic Acid

Azelaic acid is a naturally occurring saturated dicarboxylic acid which, on topical application (usually as a 20% cream), has been shown to be effective in the treatment of comedonal acne and inflammatory (papulopustular, nodular and nodulocystic) acne, as well as various cutaneous hyperpigmentary disorders characterised by hyperactive/abnormal melanocyte function, including melasma and, possibly, lentigo maligna. In addition, azelaic acid has an antiproliferative and cytotoxic effect on the human malignant melanocyte, and preliminary findings indicate that it may arrest the progression of cutaneous malignant melanoma. The mechanism of this selective cytotoxic action of azelaic acid is unclear, but may possibly be related to its inhibition of mitochondrial oxidoreductase activity and DNA synthesis. In controlled studies, topical azelaic acid demonstrated comparable anti-acne efficacy to topical tretinoin, benzoyl peroxide, erythromycin and oral tetracycline, while in patients with melasma azelaic acid proved at least as effective as topical hydroquinone. On topical application azelaic acid is well tolerated, with adverse effects apparently limited to a generally mild and transient local cutaneous irritation. Thus, topical azelaic acid, employed either as monotherapy or in combination with other treatments, is likely to prove of value in the management of acne and several hyperpigmentary disorders, most notably melasma.

Drugs. 1991 May;41(5):780-98.

DIRECTIONS

Apply evenly to the face and neck regions ensuring problematic areas have been covered. Apply in the evening and leave on overnight. Follow with AHA/BHA exfoliant or Peptide Firming Moisturiser after.

INGREDIENTS

Benzyl Alcohol, Aqua purificata, Ethanol, Azelaic Acid (10%), Propylene Glycol